Planep功效与作用

Planep (alias: eplerenone, Inspra) effects:

1. Congestive heart failure after acute myocardial infarction: Planep can improve the quality of life of patients with left ventricular dysfunction (ejection fraction ≤ 40%). Clinical trials have proven that this product can also be used for heart failure after acute myocardial infarction and congestive heart failure after acute myocardial infarction;

2. Anti-hypertensive: Planep can be used alone or in combination with other anti-hypertensive drugs for the treatment of hypertension.

The FDA has approved Planep for use in stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and congestive heart failure after acute myocardial infarction (MI) to improve survival.

Planep is the first aldosterone receptor blocker approved for this indication. The FDA's approval was based on the results of the EPHESUS (Planep Efficacy and Survival Study in Heart Failure After Acute Myocardial Infarction) trial. In patients with heart failure after myocardial infarction, Planep plus standard treatment reduced mortality by 15% compared with placebo and standard treatment (ACE inhibitors and beta blockers).

What Planep (alias: eplerenone, Inspra) does:

Lanep has a protective effect on the liver, heart disease, and kidneys without damaging the organs. Planep can promote urination without losing potassium.

Planep is a new generation of selective aldosterone antagonist. Planep can be used alone or in combination with other antihypertensive drugs for the treatment of hypertension. It also has a good antihypertensive effect on simple systolic hypertension and has a good antihypertensive effect on diet-induced obesity-related hypertension.

In addition, Planep can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for hypertensive patients with diabetes.