泽尼达妥单抗的购买渠道有哪些？

Zenidatuzumab is an innovative bispecific antibody drug for HER2-positive biliary tract cancer. Its purchase channels, usage, dosage and price are the focus of attention of patients and medical workers. This article will introduce in detail the purchasing channels, usage and dosage, and price information of zenidatuzumab to provide practical reference for patients in need.

What are the purchase channels for zenidatuzumab?

Since zenidatuzumab has not yet been launched in China, patients need to obtain the drug through specific channels. Understanding the formal purchasing channels is crucial to ensuring drug quality.

Overseas medical institutions

Patients can obtain zenidatumab through regular overseas medical institutions. Cancer hospitals or pharmacies in listed countries such as the United States and Europe are the main purchasing channels. Complete medical records and proof of prescription are required at time of purchase.

Franchised Import Procedure

Under special circumstances, Chinese patients can apply for licensed import through the hospital. This procedure requires the hospital to issue a certificate of clinical urgency and go through the import procedures in accordance with the relevant regulations of the State Food and Drug Administration.

No matter which purchasing channel is chosen, patients should keep the complete purchase receipt and drug instructions, and use them under the guidance of a professional doctor.

Usage and dosage of Zenidatuzumab

Zenidatuzumab is an intravenous infusion preparation, and its usage and dosage must strictly follow the treatment plan to reduce adverse reactions.

Patient Selection Criteria

The diagnosis of HER2-positive (IHC3+) unresectable or metastatic biliary tract cancer must be confirmed by an FDA-approved testing method before use. Patients who do not meet the indications should not use this drug.

Standard dosage regimen

The recommended dose is 20mg/kg, intravenous infusion once every 2 weeks. The first and second infusion time is controlled at 120-150 minutes, and subsequent infusion times can be gradually shortened to 60-90 minutes.

Principles for dose adjustment

The dose needs to be adjusted when left ventricular dysfunction, infusion-related reactions or severe diarrhea occur. The specific adjustment plan should be determined based on the grade of adverse reactions and patient tolerance.

During medication, cardiac function, electrolyte levels and tumor markers need to be monitored regularly, and treatment efficacy and safety must be evaluated in a timely manner.

Price of Zenidatuzumab

As an innovative biological agent, Zenidatuzumab has a relatively high price. Understanding its pricing information can help patients plan their treatment budget.

Official Pricing

The official pricing of Zenidatuzumab produced by American Jazz Company is US$13,372 per box (300mg*2 bottles). This price may vary by region and medical institution.

Additional costs

In addition to drug costs, patients also need to consider additional costs such as international transportation, tariffs, cold chain storage, etc. These costs may significantly increase the final cost of medication.

Future price changes

As the drug is approved for marketing in more countries around the world and generic drugs emerge, prices may fall in the future. Patients can pay attention to drug approval trends and grasp the best treatment opportunities.

High treatment costs may put financial pressure on patients. It is recommended to understand medical insurance policies and charity assistance projects in advance to obtain maximum financial support.