福巴替尼国内能买到吗？在哪能买到？

Forbatinib is a targeted drug used to treat patients with cholangiocarcinoma that is resistant to first-generation FGFR inhibitor treatment. It was developed by Japan's Tahoe Pharmaceuticals and has a trade name of LYTGOBI. As of now, the drug has not been approved for marketing in China, nor is it included in medical insurance, but patients can obtain generic versions through specific channels. This article will conduct a detailed analysis of the domestic purchase situation, purchase channels, and usage precautions of forbatinib.

Is forbatinib available in China?

As of June 2025, it has not been officially approved for marketing in mainland China, so regular domestic hospitals and pharmacies cannot directly purchase the original drug. Some patients can obtain the generic version of the drug produced by Lucius in Laos through special channels. The specification is 4mg*35 tablets/box and the price is about US$480.

Marketing status of the original drug

The original drug forbatinib is produced by Japan's Tahoe Pharmaceuticals. It received accelerated approval from the US FDA in October 2022 and was approved in Japan and the European Union in 2023. However, China's National Medical Products Administration (NMPA) has not completed the approval process for the drug, so domestic patients are temporarily unable to purchase the original drug through formal channels.

Availability of generic drugs

The generic drug of forbatinib produced by Lucius in Laos is currently one of the main choices for domestic patients. This generic drug is similar to the original drug in terms of ingredients and efficacy and is relatively low-priced, but it needs to be obtained through cross-border medical intermediaries or purchasing agents.

Forbatinib has not yet been officially launched in China, but generic drugs provide treatment opportunities for some patients.

Where can I buy forbatinib?

For patients who need forbatinib treatment, they can currently obtain the drug through the following channels, but they need to pay attention to the legality.

Cross-border medical service institutions

Some professional cross-border medical service institutions cooperate with overseas pharmacies or hospitals to help patients legally purchase forbatinib generic drugs. These institutions usually provide direct mailing services for drugs, accompanied by relevant drug certification documents to ensure that the source of the drugs is reliable.

Purchasing drugs overseas

Patients can purchase generic forbatinib drugs from Laos, India and other countries in person or by entrusting relatives and friends. This is another option, but there is a greater risk and you may buy counterfeit drugs.

Participate in clinical trials

Some domestic hospitals may conduct clinical trials related to forbatinib, and eligible patients can receive free drug treatment by participating in the trials. Patients can consult their attending physician or pay attention to the hospital’s official website for clinical trial recruitment information.

When purchasing forbatinib, you must choose formal channels to avoid drug quality issues that may affect the treatment effect.

Precautions for fobatinib

As a targeted drug, fobatinib must be used in strict compliance with medical instructions and the following matters must be paid attention to to reduce the risk of adverse reactions.

Dosage and time

The recommended dose of fobatinib is 20 mg (5 4 mg tablets), taken orally once a day and at a fixed time. If a dose is missed for more than 12 hours or vomiting occurs, there is no need to take a missed dose, just take the next dose as planned. Swallow tablet whole without crushing or chewing.

Adverse reaction monitoring

Forbatinib may cause retinopathy and hyperphosphatemia. An ophthalmic examination is required before treatment, and visual acuity and serum phosphate levels are monitored regularly during treatment. If blurred vision or abnormal phosphate levels occur, you need to seek medical advice promptly to adjust your medication regimen.

Drug interactions

Combined use of forbatinib with inhibitors or inducers of CYP3A and P-gp may affect the efficacy of the drug. Avoid concurrent use with strong CYP3A inhibitors (such as ketoconazole) or inducers (such as rifampicin). If other drugs need to be used in combination, the dosage needs to be adjusted under the guidance of a doctor.

The use of forbatinib requires close monitoring of adverse reactions and inappropriate drug combinations should be avoided.