英菲格拉替尼一盒多少粒,用法用量是多少？

How many pills per box of Infigratinib?

Infigratinib is an orally bioavailable pan-inhibitor of human fibroblast growth factor receptors (FGFRs) with potential anti-angiogenic and anti-tumor activity for previously treated patients with FGFR2 gene fusions or other rearrangements. For adult patients with unresectable locally advanced or metastatic cholangiocarcinoma, it was approved by the US FDA for marketing in May 2021. The specifications currently available on the market are 100mg*21 capsules + 25mg*21 capsules per box. Patients can take the medicine according to their own conditions.

What is the dosage of Infigratinib?

Before using infigratinib, it is necessary to determine whether there is FGFR2 gene fusion or rearrangement. The recommended dose is 125 mg, taken orally once a day, for 21 days of continuous treatment, and 7 days of drug withdrawal, with a 28-day treatment cycle. However, if the patient has liver damage, the dose needs to be adjusted. The recommended dose for patients with moderate liver damage is 75 mg; for patients with mild liver damage, the recommended dose is 100 mg; for patients with mild and moderate renal insufficiency, the recommended dose is 100 mg; both are administered once a day for 21 consecutive days and discontinued for 7 days, with a 28-day treatment cycle.

It is understood that the price of Infigratinib in overseas markets is about 219,600 per box, but due to exchange rate fluctuations, the price of the drug is not fixed. The specification of Infigratinib is 125mg*21 tablets, which means that you need at least one box of this product a month, and the cost is about 219,600.

At present, Infigratinib has not been officially launched in China, and patients cannot buy it in domestic hospital pharmacies. Patients who need Infigratinib can purchase it abroad, or obtain it through domestic professional overseas medical service institutions. The drug can be directly mailed to your home from overseas, and it is guaranteed to be genuine and affordable. It is recommended to consult the customer service staff for specific costs and drug purchase procedures. The drug purchase is guaranteed.

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