替莫唑胺一次能囤几盒?多少钱?

Temozolomide is used to treat newly diagnosed glioblastoma multiforme initially in combination with radiotherapy and subsequently as adjuvant therapy. Its purchase quantity and price are crucial to patients and their families. This article explores the purchase restrictions, price, and effectiveness of temozolomide, with the goal of providing useful information for patients who need this drug.

How many boxes of temozolomide can be stocked at a time

Purchase restrictions and suggestions

Temozolomide is a prescription drug, and its purchase is usually strictly regulated. The doctor will issue a corresponding prescription based on the patient's condition and treatment plan, so the one-time purchase quantity will be based on the doctor's order. Patients should follow their doctor's instructions and avoid hoarding medications.

In addition, considering the validity period and storage conditions of medicines, it is recommended that patients only purchase what they need to avoid waste or being unable to use due to expiration.

Storage requirements

Temozolomide should be stored at 2°C to 25°C and kept out of the reach of children. Correct storage conditions help maintain the stability of the drug.

The validity period of medicines is usually 36 months. Reasonable planning of purchase volume can ensure that patients can use effective medicines throughout the treatment cycle.

How much does temozolomide cost

The price of the Cipla version in India

The generic version of temozolomide produced by Cipla in India is available in two specifications: 100mg*5 pills priced at approximately US$21 per box, and 250mg*5 pills priced at approximately US$39 per box. This price setting makes treatment more affordable for more patients.

Cipla’s generic version of temozolomide is not only affordable, but has also passed bioequivalence testing, ensuring similar efficacy to the original drug.

The price of the Indian version of Hydron

In contrast, the generic version of temozolomide produced by India's Hydron offers three different specifications. Among them, the price of 100mg*5 pills is about US$38 per box, the price of 20mg*5 pills is US$34 per box, and the price of 250mg*5 pills is as high as about US$51 per box.

Although prices vary, these options provide patients with the possibility to choose the treatment that best suits their needs.

Efficacy of temozolomide

Performance in clinical trials

In clinical trials, temozolomide showed efficacy against newly diagnosed glioblastoma multiforme. The most common adverse reactions include gastrointestinal disturbances such as nausea and vomiting, which are usually mild to moderate and self-limiting or easily controlled with standard antiemetics.

Effects of long-term use

Temozolomide also shows significant efficacy in patients with recurrent or progressive glioblastoma multiforme or anaplastic astrocytoma. Studies have shown that temozolomide can prolong patient survival and improve quality of life.

In terms of gender differences, female patients may need closer monitoring of hematological parameters in some cases to address potential side effects.

No overall difference has been observed in the safety of temozolomide in elderly patients, and there is usually no need to adjust the dose. For patients with severe liver damage or renal impairment, the recommended dose of temozolomide has not yet been determined and needs to be used after careful evaluation.