阿那莫林效果怎么样

How effective is Anamorelin?

Anamorelin is an oral drug launched in Japan in April 2021. It can be used for cancer cachexia in patients with malignant tumors. A multi-center, placebo-controlled, randomized, double-blind, parallel-group study (ONO-7643-04 study) was conducted in patients with non-small cell lung cancer (NSCLC), and a multi-center, open-label, uncontrolled phase III study (ONO-7643-05 study) was conducted in patients with colorectal cancer, gastric cancer, and pancreatic cancer. The results showed that anamorelin increased body weight, increased appetite, and muscle mass in cachexia in cancer patients.

The treatment status of NSCLC (non-small cell lung cancer) patients using anamorelin at the National Cancer Center Central Hospital in Japan is as follows: As of December 2021, 47 patients have been treated. 60% of adenocarcinoma cases, 50% of stage IV cases, and 40% of recurrence cases (ArimaT, et al. JSMO2022). About half of the patients whose appetite improved had received less than one chemotherapy before, and 40% of the patients with advanced stage had an improvement in appetite, but the appetite of patients with end-stage disease was not improved. It can be seen that introducing anamorelin in the early stages of cachexia is more effective.

Safety of Anamorelin

The safety profile of anamorelin in cancer cachexia is relatively tolerable, and common adverse reactions include weakness, fatigue, anemia, thrombocytopenia, abdominal pain, atrial fibrillation, dyspnea, pneumonia, anxiety, and dyspnea. Anamorelin is a prescription drug. It is recommended that patients take the drug under the guidance of a doctor. If an intolerance reaction occurs, contact the doctor in time and receive symptomatic treatment under the guidance of the doctor.

Anamorelin can be used to treat cachexia in a variety of cancers, including malignant tumors such as non-small cell lung cancer, pancreatic cancer, gastric cancer, and colorectal cancer. It is a new, oral, selective ghrelin receptor agonist that can improve weight loss and loss of appetite in patients with cancer cachexia. The above is the content of how effective Anamorelin is. I hope it can help you!

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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