2026-01-15 06:18:33
On October 24,2025,Syndax Pharmaceuticals announced that the U.S.Food and Drug Administration(FDA)has approved Revuforj(revumenib)for the treatment of adult and pediatric patients aged 1 year and older with relapsed or refractory(R/R)acute myeloid leukemia(AML)carrying nucleolar phosphoprotein 1(NPM1)mutations and for whom there are no suitable alternative treatment options.Revuforj was previously approved in 2024 for the treatment of adult and pediatric patients aged 1 year and older with R/R acute leukemia associated with a lysine methyltransferase 2A gene(KMT2A)translocation.